Sarcopenia in people living with HIV. A review.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2022-12-28 DOI:10.24875/AIDSRev.22000010

Paola Conde-Higuera, José J Garduño-García, Alfonso J Cruz-Jentoft, Gloria G Peña-Ordónez, Gabriel G Huitrón-Bravo

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Abstract

The aim of this review is to know the current status of sarcopenia in people living with acquired immunodeficiency virus, as well as predictors, prevalence, and associated factors. Searches were done in PubMed, Scielo, and ScienceDirect databases (January 2010 to August 2021), using predefined search terms. Prevalence, intervention, and meta-analysis studies investigating sarcopenia or muscle mass and function in people living with Human immunodeficiency virus (PLHIV) were selected. We identified reports of high prevalence and increased risk for sarcopenia due to factors such as prolonged exposure to antiretroviral drugs, lack of physical activity, central obesity, drug use, and other sociodemographic factors, as well as disease duration. HIV should be considered a risk factor for sarcopenia, and evaluation of sarcopenia should be included as part of the comprehensive medical care of PLHIV. Forceful actions are required to prevent muscle weakness, especially in stages before old age with actions aimed at preserving strength and function.

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艾滋病毒感染者的肌肉减少症。复习一下。

本综述的目的是了解获得性免疫缺陷病毒感染者肌肉减少症的现状，以及预测因素、患病率和相关因素。检索在PubMed、Scielo和ScienceDirect数据库中完成(2010年1月至2021年8月)，使用预定义的搜索词。我们选择了调查人类免疫缺陷病毒(PLHIV)感染者肌肉减少症或肌肉质量和功能的流行率、干预和荟萃分析研究。我们确定了由于长期接触抗逆转录病毒药物、缺乏身体活动、中枢性肥胖、药物使用和其他社会人口因素以及疾病持续时间等因素导致的肌肉减少症高患病率和风险增加的报告。艾滋病毒应被视为肌肉减少症的一个危险因素，肌肉减少症的评估应作为艾滋病毒感染者综合医疗护理的一部分。需要有力的动作来防止肌肉无力，特别是在老年之前的阶段，以保持力量和功能为目的的动作。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.

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