[Alternative methods of therapy for comorbid sleep disorders as a method of choice in adult patients with epilepsy].

A G Zhidik, A B Kozhokaru
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Abstract

Objective: Systematization and generalization of data from domestic and foreign literature on alternative methods of treatment of sleep disorders in epilepsy.

Material and methods: The search for data from domestic and foreign literary sources was carried out in the electronic databases Medline (PubMed), Scopus, Web of Science, eLibrary, CyberLeninka, Google Scholar.

Results: The data of modern randomized trials, meta-analyzes on the effectiveness of various non-traditional methods as a method of choice for epilepsy with comorbid sleep disorders have been analyzed.

Conclusions: Complementary (alternative) treatments have many advantages over the classical pharmacotherapy of sleep disorders in epilepsy, in the form of non-invasiveness, low incidence of side-effects, ease of use, and lack of a dose-dependent effect. Of course, the targets of most of the above methods are not focused and not very specific, and the sample size is too small to obtain impartial and meaningful clinical conclusions, but this once again emphasizes the urgent need for large-scale clinical trials, which is necessary to develop evidence-based treatments for comorbid sleep disorders in epilepsy.

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【成人癫痫患者共病性睡眠障碍的替代治疗方法】。
目的:整理归纳国内外关于癫痫睡眠障碍替代治疗方法的文献资料。材料与方法:在Medline (PubMed)、Scopus、Web of Science、eLibrary、CyberLeninka、Google Scholar等电子数据库中检索国内外文献资料。结果:分析了现代随机试验、meta分析的数据,分析了各种非传统方法作为癫痫合并睡眠障碍的选择方法的有效性。结论:与传统药物治疗相比,补充(替代)治疗癫痫睡眠障碍具有无创、副作用发生率低、使用方便、无剂量依赖等优点。当然,上述大多数方法的目标并不集中,也不是很具体,样本量也太小,无法获得公正而有意义的临床结论,但这再次强调了大规模临床试验的迫切需要,这对于开发癫痫共病睡眠障碍的循证治疗方法是必要的。
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来源期刊
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova Medicine-Psychiatry and Mental Health
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