Arthritis remission with partial cartilage restoration in a 9-year-old female with hip chondrolysis following treatment with adalimumab.

Lampros Fotis, Anastasios Kanellopoulos, Olympia Papakonstantinou
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Abstract

Hip chondrolysis is observed primarily or secondary to other diseases and is a rare but yet debilitating disease, characterised by loss of cartilage of the femoral epiphysis and significant restriction of motion. We present the case of a 9-year-old female diagnosed with hip chondrolysis associated with probable juvenile psoriatic arthritis. Avoidance of weight-bearing activities and treatment with corticosteroids, methotrexate, and adalimumab followed by aquatic therapy resulted in clinical and radiographic improvement as well as partial cartilage regeneration.

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阿达木单抗治疗后髋关节软骨松解的9岁女性关节炎缓解伴部分软骨修复。
髋关节软骨松解主要或继发于其他疾病,是一种罕见但使人衰弱的疾病,其特征是股骨骨骺软骨丢失和明显的运动受限。我们提出的情况下,9岁的女性诊断为髋关节软骨松解与可能的青少年银屑病关节炎。避免负重活动,用皮质类固醇、甲氨蝶呤和阿达木单抗治疗,然后进行水生治疗,导致临床和影像学改善以及部分软骨再生。
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