Efficacy of topical galbanum oil with dry cupping in hospitalized COVID-19 patients: A randomized open-label clinical trial.

IF 1.9 Q3 CHEMISTRY, MEDICINAL Avicenna Journal of Phytomedicine Pub Date : 2023-07-01 DOI:10.22038/AJP.2023.21829
Fateme Seydi, Mohammadreza Salehi, Fataneh Hashem-Dabaghian, Fatemeh Emadi, Mohammad Gholami-Fesharaki, Maryam Iranzadasl
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Abstract

Objective: This study was designed to detect the therapeutic effects of galbanum oil plus dry cupping (a Persian medicine-based method) in hospitalized patients with coronavirus disease-2019 (COVID-19).

Materials and methods: In this randomized controlled trial, 60 hospitalized COVID-19 patients with positive polymerase chain reaction test (PCR), pulmonary involvement and blood oxygen saturation (SpO2) ≤93 mmHg, were randomly assigned into two groups to take the standard therapeutic regimen alone or alongside cupping and topical galbanum oil (Ferula gommosa oleo-gum resin) for 3-5 days. The SpO2 level, the severity of signs and symptoms of patients and laboratory parameters were compared between the two groups.

Results: Fifty-eight patients were analyzed. The SpO2 level changed from 89.27±3.82 to 90.29±3.09 mmHg (p=0.038) in control group, while it increased from 88.74±3.45 to 94.23±2.1 mmHg (<0.001) in galbanum group with a significant difference between the groups (p<0.001). Fever, cough, dyspnea, and anorexia alleviated in the galbanum group more than the control (p=0.003, 0.001, 0.01, and 0.04, respectively). No adverse effects were reported due to galbanum oil and cupping therapy.

Conclusion: Dry cupping with galbanum oil alongside the routine therapeutic regimen could be more effective than the routine therapeutic regimen alone for improving SpO2 level and alleviating fever, cough, and dyspnea in COVID-19 patients.

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局部加尔巴油与干式拔罐治疗新冠肺炎住院患者的疗效:一项随机开放性临床试验。
目的:本研究旨在检测加尔巴农油加干拔罐(波斯医学方法)对2019冠状病毒病(新冠肺炎)住院患者的治疗效果。材料与方法:在本随机对照试验中,将60例聚合酶链式反应(PCR)阳性、肺部受累、血氧饱和度(SpO2)≤93 mmHg的新冠肺炎住院患者随机分为两组,分别单独或配合拔罐和局部加尔巴油(Ferula gommosa oleo-gum resin)治疗3-5天。比较两组患者的SpO2水平、体征和症状的严重程度以及实验室参数。结果:对58例患者进行了分析。对照组SpO2由89.27±3.82 mmHg增至90.29±3.09 mmHg(p=0.038),由88.74±3.45 mmHg增至94.23±2.1 mmHg。
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来源期刊
Avicenna Journal of Phytomedicine
Avicenna Journal of Phytomedicine CHEMISTRY, MEDICINAL-
CiteScore
3.40
自引率
4.50%
发文量
17
审稿时长
6 weeks
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