Thromboelastometry-guided surgery in neuroblastoma complicated with disseminated intravascular coagulation.

Q3 Medicine Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica Pub Date : 2023-01-01 DOI:10.54847/cp.2023.01.20

M R Pérez-Torres Lobato, M Molina Mata, M L Llempen López, I Fernández-Pineda, R M Cabello Laureano, J Rodríguez Martorell

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Abstract

Background: Disseminated intravascular coagulation (DIC) is a rare oncological emergency. We report a pediatric neuroblastoma complicated with DIC which required thromboelastometry-guided surgery.

Observation: A 6-year-old female diagnosed with intermediate risk adrenal neuroblastoma developed tumor-related DIC after chemotherapy first cycle. She remained stable without clinical bleeding and emergent tumor resection guided by intraoperative-thromboelastometry was decided. DIC resolved early after surgery and complete remission was achieved.

Conclusion: Treatment of the underlying condition is critical to manage DIC. Thromboelastometry can guide goal-directed therapy, including surgery in pediatric patients. However, larger studies are needed to examine its applicability in different clinical settings, such as cancer related DIC.

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血栓弹性测量引导下神经母细胞瘤合并弥散性血管内凝血的手术治疗。

背景:弥散性血管内凝血(DIC)是一种罕见的肿瘤急症。我们报告一例小儿神经母细胞瘤合并DIC，需要血栓弹性测量指导手术。观察:一名6岁女性，诊断为中度危险肾上腺神经母细胞瘤，在化疗第一周期后发生肿瘤相关性DIC。她保持稳定，无临床出血，并决定在术中血栓弹性测量术指导下紧急切除肿瘤。DIC在术后早期消退，完全缓解。结论:治疗基础疾病是控制DIC的关键。血栓弹性测量可以指导目标导向的治疗，包括儿科患者的手术。然而，需要更大规模的研究来检验其在不同临床环境中的适用性，例如与癌症相关的DIC。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica Medicine-Medicine (all)

CiteScore

1.40

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0.00%

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