Hyperfunctioning Intrathyroidal Parathyroid: a Misleading Preoperative Diagnosis.

IF 2.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Nuclear Medicine and Molecular Imaging Pub Date : 2023-02-01 Epub Date: 2022-11-19 DOI:10.1007/s13139-022-00783-1
Josefina Carullo, Jacob Bani, Gerlinde Averous, Mehdi Helali, Celine Heimburger, Michel Vix, Alessio Imperiale
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Abstract

Hyperfunctioning parathyroid glands may be rarely located in the thyroidal parenchyma and not identified by imaging or during surgical procedures. We present three patients with primary hyperparathyroidism related to hyperfunctioning intrathyroidal parathyroid retrospectively selected among 732 cases from own Institutional parathyroid PET/CT registry from 2018 to 2022. Intrathyroidal parathyroids showed intense 18F-fluorocholine uptake but a variable echographic pattern, inconstant 99mTc-MIBI uptake, and atypic iodine-contrast enhancement. Although rare, the possibility of an intrathyroidal parathyroid should be considered when no hyperfunctioning gland is found on preoperative imaging and thorough bilateral neck exploration.

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甲状旁腺功能亢进:误导性术前诊断
功能亢进的甲状旁腺可能极少位于甲状腺实质内,在影像学检查或手术过程中无法发现。我们从2018年至2022年本机构甲状旁腺PET/CT登记的732例病例中回顾性筛选出3例与甲状旁腺功能亢进相关的原发性甲状旁腺功能亢进症患者。甲状旁腺内甲状旁腺表现为强烈的18F-氟胆碱摄取,但回声图模式不一,99m锝-MIBI摄取不稳定,碘对比增强不典型。尽管这种情况很少见,但如果在术前成像和双侧颈部彻底探查时未发现功能亢进的腺体,则应考虑甲状旁腺内的可能性。
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来源期刊
Nuclear Medicine and Molecular Imaging
Nuclear Medicine and Molecular Imaging RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
2.20
自引率
7.70%
发文量
58
期刊介绍: Nuclear Medicine and Molecular Imaging (Nucl Med Mol Imaging) is an official journal of the Korean Society of Nuclear Medicine, which bimonthly publishes papers on February, April, June, August, October, and December about nuclear medicine and related sciences such as radiochemistry, radiopharmacy, dosimetry and pharmacokinetics / pharmacodynamics of radiopharmaceuticals, nuclear and molecular imaging analysis, nuclear and molecular imaging instrumentation, radiation biology and radionuclide therapy. The journal specially welcomes works of artificial intelligence applied to nuclear medicine. The journal will also welcome original works relating to molecular imaging research such as the development of molecular imaging probes, reporter imaging assays, imaging cell trafficking, imaging endo(exo)genous gene expression, and imaging signal transduction. Nucl Med Mol Imaging publishes the following types of papers: original articles, reviews, case reports, editorials, interesting images, and letters to the editor. The Korean Society of Nuclear Medicine (KSNM) KSNM is a scientific and professional organization founded in 1961 and a member of the Korean Academy of Medical Sciences of the Korean Medical Association which was established by The Medical Services Law. The aims of KSNM are the promotion of nuclear medicine and cooperation of each member. The business of KSNM includes holding academic meetings and symposia, the publication of journals and books, planning and research of promoting science and health, and training and qualification of nuclear medicine specialists.
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