Adsorption of insulin onto neonatal infusion sets: should intravenous administration of insulin to treat hyperglycemia in preterm babies on the NICU be proceeded by priming of the intravenous system, adding of albumin, or non-priming to get to a stable insulin dose?

IF 2.4 Q1 PEDIATRICS Molecular and cellular pediatrics Pub Date : 2022-12-21 DOI:10.1186/s40348-022-00154-y
Paola Mian, Mathieu S Bolhuis, J Marina Maurer, Margriet van Stuijvenberg
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Abstract

Insulin is used to treat neonatal hyperglycaemia when blood glucose concentrations are consistently high, and to treat neonatal diabetes. Within this brief report, a review of the existing literature is conducted to determine if intravenous administration of insulin should be proceeded by priming of the intravenous system, adding of albumin, or non-priming to get a stable insulin dose. Within this literature search, we focused on experimental insulin adsorption data (in vitro studies).

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胰岛素在新生儿输液器上的吸附:新生儿重症监护病房早产儿静脉注射胰岛素治疗高血糖是否应该通过启动静脉系统、添加白蛋白或不启动来获得稳定的胰岛素剂量?
当血糖浓度持续偏高时,胰岛素用于治疗新生儿高血糖,并用于治疗新生儿糖尿病。在这篇简短的报告中,对现有文献进行了回顾,以确定静脉注射胰岛素是否应该通过静脉系统启动、添加白蛋白或不启动来获得稳定的胰岛素剂量。在本文献检索中,我们重点关注实验性胰岛素吸附数据(体外研究)。
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