Intermittent Subcutaneous Injections of Apomorphine in Parkinson's Disease.

IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL Eurasian Journal of Medicine Pub Date : 2022-12-01 DOI:10.5152/eurasianjmed.2022.22134
Mustafa Ceylan, Murat Gültekin, Nazlı Durmaz Çelik, Bedia Samanci, Gül Yalçin Çakmakli, Rezzak Yilmaz
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Abstract

The intermittent subcutaneous injection of apomorphine is highly effective in the management of motor and non-motor symptoms of Parkinson's disease. Although it has been shown that apomorphine injection can be safely used in selected cases at all stages of the disease, there is no consensus regarding intermittent administration strategies. This review aimed to discuss the indications for intermittent subcutaneous apomorphine use in clinical practice, possible side effects and their management, and contraindicated cases in light of the literature and to present practical recommendations for clinical practice.

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间歇性皮下注射阿朴吗啡治疗帕金森病
间歇性皮下注射阿朴吗啡对治疗帕金森病的运动和非运动症状非常有效。虽然已有研究表明,阿朴吗啡注射可安全用于疾病各阶段的特定病例,但对于间歇性给药策略尚未达成共识。本综述旨在结合文献,讨论间歇性皮下注射阿扑吗啡在临床实践中的适应症、可能出现的副作用及其处理、禁忌病例,并为临床实践提出切实可行的建议。
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来源期刊
Eurasian Journal of Medicine
Eurasian Journal of Medicine Medicine-Medicine (all)
CiteScore
1.90
自引率
6.70%
发文量
59
审稿时长
16 weeks
期刊介绍: Eurasian Journal of Medicine (Eurasian J Med) is an international, scientific, open access periodical published by independent, unbiased, and triple-blinded peer-review principles. The journal is the official publication of Atatürk University School of Medicine and published triannually in February, June, and October. The publication language of the journal is English. The aim of the Eurasian Journal of Medicine is to publish original research papers of the highest scientific and clinical value in all medical fields. The Eurasian J Med also includes reviews, editorial short notes and letters to the editor that either as a comment related to recently published articles in our journal or as a case report. The target audience of the journal includes researchers, physicians and healthcare professionals who are interested or working in in all medical disciplines.
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