Synthesis of quercetin-functionalized silver nanoparticles by rapid one-pot approach.

Abstract

Nanotechnology plays a pivotal role in all areas of science, and the synthesis and surface modification of nanoparticles are crucial in this field. Metal nanoparticles synthesized using plant extracts or phytocompounds are highly significant in the development of various therapeutics and diagnostics. In the present study, we report the one-pot and rapid synthesis of silver nanoparticles (AgNPs) by quercetin, a flavonoid found in various edible plants. The nanoparticles were then characterized using UV-VIS spectrophotometry, Fourier-transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The role of quercetin in the synthesis of silver nanoparticles was demonstrated. The nanomaterial was 20-30 nm in size and spherical in shape. The silver nanoparticles were also confirmed to show antioxidant activity at 80 μg/ml concentration in vitro by DPPH, FRAP, and power reduction methods.