SMARCB1(INI-1)-Deficient Sinonasal Carcinoma: An Evolving Entity.

IF 0.7 Q4 CLINICAL NEUROLOGY Journal of Neurological Surgery Reports Pub Date : 2023-01-01 DOI:10.1055/a-1996-1283
Sei Y Chung, Parker Kenee, Tanner Mitton, Ashleigh Halderman
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Abstract

SMARCB1(INI-1)-deficient sinonasal carcinoma is a rare, poorly differentiated neoplasm with a poor prognosis. Though historically most were identified as sinonasal undifferentiated carcinoma, we now understand it to be a distinct entity. There is currently a general consensus supporting multimodal therapy, though the optimal sequence of surgery, chemotherapy, and radiation has yet to be defined.

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SMARCB1(ni -1)-缺陷鼻窦癌:一个进化的实体。
SMARCB1(ni -1)缺陷鼻窦癌是一种罕见的低分化肿瘤,预后差。虽然历史上大多数被确定为鼻窦未分化癌,但我们现在理解它是一个独特的实体。尽管手术、化疗和放疗的最佳顺序尚未确定,但目前普遍支持多模式治疗。
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