Ideal Features of Topical Antibiotic Therapy for the Treatment of Impetigo: An Italian Expert Consensus Report

IF 1.6 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Current Therapeutic Research-clinical and Experimental Pub Date : 2023-01-01 DOI:10.1016/j.curtheres.2022.100690

Iria Neri MD , Michele Miraglia del Giudice MD , Andrea Novelli MD , Giuseppe Ruggiero MD , Giovanni Pappagallo MD, MPH , Luisa Galli MD

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引用次数: 1

Abstract

Background

A group of Italian experts in impetigo medical care sought to define 10 statements to describe the ideal characteristics of the best local antibiotic treatments, and to provide relevant information re- garding their appropriate use and prescription that should be considered in clinical practice for impetigo management.

Objective

A group of Italian experts in impetigo medical care sought to define 10 statements to describe the ideal characteristics of the best local antibiotic treatments, and to provide relevant information regarding their appropriate use and prescription that should be considered in clinical practice for impetigo management.

Methods

A consensus on ideal features of antibiotic therapy for the treatment of impetigo was appraised by an online Delphi-based method, based on a panel of 61 infectious disease specialists, pediatricians, and dermatologists coordinated by a scientific committee of 5 experts specializing in impetigo management.

Results

Full or very high consensus was reached on the 10 statements identified to describe the characteristics of the best hypothetic antibiotic therapy for impetigo together with indications for appropriate antibiotics use.

Conclusions

Several criteria have to be considered when selecting topical antibacterial therapy for impetigo. Beyond efficacy and safety, antimicrobial susceptibility and pharmacological characteristics of the agent are essential points. Formulation of the antimicrobial product is fundamental, as well as patient and caregiver preference, to facilitate therapeutic adherence, to achieve the infection control, and to obtain the best benefit from treatment (Curr Ther Res Clin Exp. 2023; 84:XXXXXX).

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局部抗生素治疗脓疱疮的理想特征:意大利专家共识报告

背景一组意大利脓疱病医疗专家试图定义10种陈述，以描述当地最佳抗生素治疗的理想特征，并提供有关其适当使用和处方的相关信息，这些信息应在临床实践中考虑用于脓疱病治疗。目的一组意大利脓疱病医疗专家试图定义10种陈述，以描述当地最佳抗生素治疗的理想特征，并提供有关其适当使用和处方的相关信息，这些信息应在临床实践中用于脓疱病治疗。方法由61名传染病专家、儿科医生和皮肤科医生组成的小组，在5名专门研究脓疱病管理的专家组成的科学委员会的协调下，采用基于德尔菲的在线方法，对抗生素治疗脓疱病的理想特征进行评估。结果对描述脓疱病最佳假设抗生素治疗的特征以及适当使用抗生素的适应症的10项声明达成了完全或非常高的共识。结论在选择局部抗菌治疗脓疱病时，必须考虑几个标准。除了有效性和安全性之外，该药物的抗微生物敏感性和药理学特性也是关键。抗菌产品的配方以及患者和护理人员的偏好是促进治疗依从性、实现感染控制和从治疗中获得最佳益处的基础（Curr Ther Res Clin Exp.2023；84:XXXXXX）。

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来源期刊

Current Therapeutic Research-clinical and Experimental 医学-药学

CiteScore

3.50

自引率

0.00%

发文量

审稿时长

3 months

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