Filippo Migliorini, Gianluca Vecchio, Christian David Weber, Daniel Kämmer, Andreas Bell, Nicola Maffulli
{"title":"Management of transient bone osteoporosis: a systematic review.","authors":"Filippo Migliorini, Gianluca Vecchio, Christian David Weber, Daniel Kämmer, Andreas Bell, Nicola Maffulli","doi":"10.1093/bmb/ldad012","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Transient bone osteoporosis (TBO) is characterized by persistent pain, loss of function, no history of trauma and magnetic resonance image (MRI) findings of bone marrow edema.</p><p><strong>Source of data: </strong>PubMed, Google scholar, EMABSE and Web of Science were accessed in February 2023. No time constrains were used for the search.</p><p><strong>Areas of agreement: </strong>TBO is rare and misunderstood, typically affecting women during the third trimester of pregnancy or middle-aged men, leading to functional disability for 4-8 weeks followed by self-resolution of the symptoms.</p><p><strong>Areas of controversy: </strong>Given the limited evidence in the current literature, consensus on optimal management is lacking.</p><p><strong>Growing points: </strong>This systematic review investigates current management of TBO.</p><p><strong>Areas timely for developing research: </strong>A conservative approach leads to the resolution of symptoms and MRI findings at midterm follow-up. Administration of bisphosphonates might alleviate pain and accelerate both clinical and imaging recovery.</p>","PeriodicalId":9280,"journal":{"name":"British medical bulletin","volume":"147 1","pages":"79-89"},"PeriodicalIF":6.7000,"publicationDate":"2023-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10788841/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"British medical bulletin","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/bmb/ldad012","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: Transient bone osteoporosis (TBO) is characterized by persistent pain, loss of function, no history of trauma and magnetic resonance image (MRI) findings of bone marrow edema.
Source of data: PubMed, Google scholar, EMABSE and Web of Science were accessed in February 2023. No time constrains were used for the search.
Areas of agreement: TBO is rare and misunderstood, typically affecting women during the third trimester of pregnancy or middle-aged men, leading to functional disability for 4-8 weeks followed by self-resolution of the symptoms.
Areas of controversy: Given the limited evidence in the current literature, consensus on optimal management is lacking.
Growing points: This systematic review investigates current management of TBO.
Areas timely for developing research: A conservative approach leads to the resolution of symptoms and MRI findings at midterm follow-up. Administration of bisphosphonates might alleviate pain and accelerate both clinical and imaging recovery.
简介：短暂性骨质疏松症（TBO）的特点是持续疼痛、功能丧失、无创伤史和骨髓水肿的磁共振成像（MRI）表现。数据来源：PubMed、谷歌学者、EMABSE和Web of Science于2023年2月访问。搜索没有使用时间限制。一致的领域：TBO是一种罕见且被误解的疾病，通常影响妊娠晚期的女性或中年男性，导致4-8周的功能残疾，然后症状自行缓解。争议领域：鉴于当前文献中的证据有限，缺乏关于最佳管理的共识。成长点：这篇系统综述调查了TBO的当前管理。及时开展研究的领域：保守的方法可以在中期随访中解决症状和MRI结果。服用双膦酸盐可能减轻疼痛，加速临床和影像学恢复。
期刊介绍：
British Medical Bulletin is a multidisciplinary publication, which comprises high quality reviews aimed at generalist physicians, junior doctors, and medical students in both developed and developing countries.
Its key aims are to provide interpretations of growing points in medicine by trusted experts in the field, and to assist practitioners in incorporating not just evidence but new conceptual ways of thinking into their practice.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
