Antiviral performance of graphene-based materials with emphasis on COVID-19: A review

Tahereh Seifi, Ali Reza Kamali
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引用次数: 35

Abstract

Coronavirus disease-2019 has been one of the most challenging global epidemics of modern times with a large number of casualties combined with economic hardships across the world. Considering that there is still no definitive cure for the recent viral crisis, this article provides a review of nanomaterials with antiviral activity, with an emphasis on graphene and its derivatives, including graphene oxide, reduced graphene oxide and graphene quantum dots. The possible interactions between surfaces of such nanostructured materials with coronaviruses are discussed. The antiviral mechanisms of graphene materials can be related to events such as the inactivation of virus and/or the host cell receptor, electrostatic trapping and physico-chemical destruction of viral species. These effects can be enhanced by functionalization and/or decoration of carbons with species that enhances graphene-virus interactions. The low-cost and large-scale preparation of graphene materials with enhanced antiviral performances is an interesting research direction to be explored.

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以新型冠状病毒为重点的石墨烯基材料抗病毒性能研究进展
2019冠状病毒病是现代最具挑战性的全球流行病之一,造成大量人员伤亡,加上世界各地的经济困难。考虑到最近的病毒危机仍然没有明确的治愈方法,本文综述了具有抗病毒活性的纳米材料,重点介绍了石墨烯及其衍生物,包括氧化石墨烯、还原氧化石墨烯和石墨烯量子点。讨论了这种纳米结构材料表面与冠状病毒之间可能的相互作用。石墨烯材料的抗病毒机制可能与病毒和/或宿主细胞受体的失活、静电捕获和病毒物种的物理化学破坏等事件有关。这些效应可以通过碳的官能化和/或修饰来增强石墨烯与病毒的相互作用。低成本、大规模制备具有增强抗病毒性能的石墨烯材料是一个值得探索的有趣研究方向。
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来源期刊
Medicine in Drug Discovery
Medicine in Drug Discovery Medicine-Pharmacology (medical)
CiteScore
8.30
自引率
0.00%
发文量
30
审稿时长
21 days
期刊介绍:
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