Vogt-Koyanagi-Harada Disease: A Case Series in a Tertiary Eye Center.

IF 0.7 Q4 OPHTHALMOLOGY Case Reports in Ophthalmological Medicine Pub Date : 2021-01-01 DOI:10.1155/2021/8848659
Pranav Shrestha, Sadhana Sharma, Ranju Kharel
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引用次数: 2

Abstract

Purpose: To study the clinical spectrum of Vogt-Koyanagi-Harada (VKH) disease in a tertiary eye center in Nepal.

Methods: Baseline demographic details and clinical features of six patients diagnosed as VKH in a tertiary eye center were retrospectively reviewed. Examinations included best corrected visual acuity, intraocular pressure, and slit lamp examination of anterior and posterior segments. Baseline blood investigations, chest X-ray, fundus photography, and fundus fluorescent angiography (FFA) were performed on all the patients.

Results: The mean age at presentation was 46 ± 8.43 years with female predominance (83.3%). The disease was complete in 16.7%, incomplete in 16.7%, and probable in 66.7% of the patients. Most cases presented in acute uveitis stage (66.7%). The most common finding in acute cases was serous retinal detachment (66.7%), followed by disc edema (58.3%), whereas in chronic cases, depigmented fundus was the most common. All cases had bilateral presentation.

Conclusion: VKH is an important cause of bilateral loss of vision and has a good visual prognosis if aggressive treatment is initiated during the early stages.

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Vogt-Koyanagi-Harada病:三级眼科中心的病例系列。
目的:研究尼泊尔某三级眼科中心Vogt-Koyanagi-Harada (VKH)病的临床特征。方法:回顾性分析某三级眼科中心诊断为VKH的6例患者的基线人口学资料和临床特征。检查包括最佳矫正视力、眼压、裂隙灯检查前、后节。对所有患者进行基线血液检查、胸部x线、眼底摄影和眼底荧光血管造影(FFA)。结果:平均发病年龄为46±8.43岁,以女性为主(83.3%)。完全病变占16.7%,不完全病变占16.7%,可能病变占66.7%。以急性葡萄膜炎为主(66.7%)。急性病例中最常见的是浆液性视网膜脱离(66.7%),其次是椎间盘水肿(58.3%),而慢性病例中最常见的是眼底色素沉着。所有病例均为双侧表现。结论:VKH是双侧视力丧失的重要原因,早期积极治疗,预后良好。
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审稿时长
14 weeks
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