A Presentation of Synchronous Ovarian and Endometrial Endometrioid Adenocarcinoma From a Case of Suspected Ruptured Ectopic Pregnancy.

Siak Ming Goh, Yanlin Carly Wu, Ryan Wai Kheong Lee
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Abstract

A 32-year-old woman of child-bearing age who initially underwent surgical laparoscopy for suspected ruptured ectopic pregnancy with elevated serum β-human chorionic gonadotropin (hCG) levels was unexpectedly found to have histologically diagnosed synchronous ovarian and endometrial endometrioid adenocarcinoma. She subsequently underwent another full completion staging surgery and adjuvant chemotherapy as she was unsuitable for fertility-sparing surgery. An elevated serum β-hCG level accompanied by clinical signs of acute abdominal pain, per vaginal bleeding, ultrasound features of abdominal free fluid in the pelvis and an adnexal mass warrants a high clinical suspicion for a ruptured ectopic pregnancy. However, it is important to recognize ovarian malignancy as a rare but differential diagnosis to suspected ectopic pregnancy in patients with acute abdomen. Fertility-sparing surgery may be considered for young patients seeking fertility, without compromising patient survival in women without synchronous gynecological cancers.

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怀疑宫外孕破裂并发卵巢及子宫内膜样腺癌1例。
一名32岁的育龄妇女,最初因怀疑宫外孕破裂并血清β-人绒毛膜促性腺激素(hCG)水平升高而接受腹腔镜手术,却意外地发现组织学诊断为同步卵巢和子宫内膜子宫内膜样腺癌。由于不适合保留生育能力的手术,她随后接受了另一次完全完成分期手术和辅助化疗。血清β-hCG水平升高,伴有急性腹痛、阴道出血、超声显示骨盆内游离液体和附件肿块等临床症状,临床高度怀疑是宫外孕破裂。然而,重要的是要认识到卵巢恶性肿瘤是一个罕见的,但鉴别诊断怀疑异位妊娠急腹症患者。对于寻求生育能力的年轻患者,可以考虑保留生育能力的手术,而不会影响没有同步妇科癌症的患者的生存。
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