Lymphopenia during 177Lu-DOTATATE therapy leading to recurrence of tuberculosis: a case report.

IF 1.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING European Journal of Hybrid Imaging Pub Date : 2022-12-13 DOI:10.1186/s41824-022-00157-y
Sarah Boughdad, Michael Da Mota, Mélanie Mendes De Carvalho, Maria Firsova, John O Prior, Niklaus Schaefer
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Abstract

We report the case of a 72-year-old woman who presented with tuberculous arthritis during the setting of 177Lu-DOTATATE therapy for a grade-2 neuro-endocrine pancreatic tumor with liver metastases. We hypothesized that this recurrence might have been related to the occurrence of lymphopenia, which is common during PRRT. Indeed, though lymphopenia is frequently dismissed, it could lead to the development of opportunistic diseases and its severity should be examined, especially in case of abnormal clinical symptoms.

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177Lu-DOTATATE治疗期间淋巴细胞减少导致结核复发:1例报告。
我们报告一例72岁的妇女,她在接受177Lu-DOTATATE治疗伴有肝转移的2级胰腺神经内分泌肿瘤时出现结核性关节炎。我们假设这种复发可能与PRRT期间常见的淋巴细胞减少的发生有关。事实上,虽然淋巴细胞减少症经常被忽视,但它可能导致机会性疾病的发展,应检查其严重程度,特别是在出现异常临床症状的情况下。
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来源期刊
European Journal of Hybrid Imaging
European Journal of Hybrid Imaging Computer Science-Computer Science (miscellaneous)
CiteScore
3.40
自引率
0.00%
发文量
29
审稿时长
17 weeks
期刊最新文献
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