Synthesis approach-dependent antiviral properties of silver nanoparticles and nanocomposites.

IF 8.6 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Journal of Nanostructure in Chemistry Pub Date : 2022-01-01 DOI:10.1007/s40097-021-00465-y

Jaison Jeevanandam, Saravanan Krishnan, Yiik Siang Hii, Sharadwata Pan, Yen San Chan, Caleb Acquah, Michael K Danquah, João Rodrigues

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引用次数: 36

Abstract

Numerous viral infections are common among humans, and some can lead to death. Even though conventional antiviral agents are beneficial in eliminating viral infections, they may lead to side effects or physiological toxicity. Silver nanoparticles and nanocomposites have been demonstrated to possess inhibitory properties against several pathogenic microbes, including archaea, bacteria, fungi, algae, and viruses. Its pronounced antimicrobial activity against various microbe-mediated diseases potentiates its use in combating viral infections. Notably, the appropriated selection of the synthesis method to fabricate silver nanoparticles is a major factor for consideration as it directly impacts antiviral efficacy, level of toxicity, scalability, and environmental sustainability. Thus, this article presents and discusses various synthesis approaches to produce silver nanoparticles and nanocomposites, providing technological insights into selecting approaches to generate antiviral silver-based nanoparticles. The antiviral mechanism of various formulations of silver nanoparticles and the evaluation of its propensity to combat specific viral infections as a potential antiviral agent are also discussed.

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银纳米颗粒和纳米复合材料的合成方法依赖性抗病毒特性。

许多病毒感染在人类中很常见，有些会导致死亡。尽管传统的抗病毒药物对消除病毒感染是有益的，但它们可能导致副作用或生理毒性。银纳米颗粒和纳米复合材料已被证明具有抑制几种病原微生物的特性，包括古细菌、细菌、真菌、藻类和病毒。其对各种微生物介导的疾病的显著抗菌活性增强了其在对抗病毒感染方面的应用。值得注意的是，适当选择合成方法来制造纳米银是一个主要的考虑因素，因为它直接影响抗病毒功效、毒性水平、可扩展性和环境可持续性。因此，本文提出并讨论了生产银纳米颗粒和纳米复合材料的各种合成方法，为选择生产抗病毒银基纳米颗粒的方法提供了技术见解。本文还讨论了各种银纳米颗粒配方的抗病毒机制，并评价了其作为潜在抗病毒药物对抗特定病毒感染的倾向。图形化的简介:

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来源期刊

Journal of Nanostructure in Chemistry Multiple-

CiteScore

18.20

自引率

3.00%

发文量

审稿时长

22 days

期刊介绍： The Journal of Nanostructure in Chemistry (JNC) publishes cutting-edge research at the intersections of chemistry, biology, biotechnology, materials science, physics, and engineering. It features high-quality research, perspectives, and review articles covering various disciplines within the natural sciences, biomedicine, and engineering. The journal's scope includes, but is not limited to, the following topics: Target drug and gene delivery Tissue engineering and regenerative medicine Cancer therapy Diagnosis and Bioimaging Electrochemical detection and sensing Food industry and packaging Environments (catalyst, coatings, and water treatment) Energy (fuel cells, capacitor, laser)