Biological Importance, Therapeutic Benefits, and Analytical Aspects of Active Flavonoidal Compounds 'Corylin' from Psoralea corylifolia in the Field of Medicine.

Abstract

BACKGROUND Flavonoidal class phytochemicals are the best examples of secondary metabolite found to be present in the different natural sources, including 'fruits, grains, vegetables, broccoli, tea, berries, wine, strawberries, apple, grapes, lettuce and citrus fruit. Natural products are the rich source of flavonoidal compounds present in our diet source. OBJECTIVE Flavonoidal class chemical can be sub categorized into chalcones, isoflavone, flavonols, catechin, flavones, flavanones, and anthocyanidin with respect to their basic chemical structures. Psoralea corylifolia L. belongs to the family Fabaceae is an herbal medicine used in traditional Chinese Medicine for the treatment of inflammatory disorders, bacterial infections and cancerous disorders. METHODS In the present work, scientific data has been collected from different databases and analyzed in order to know the therapeutic potential of corylin in medicine. Different scientific databases such as Google, Scopus, PubMed, Science Direct etc., have been searched to collect the needed scientific information of corylin. Scientific information of corylin has been collected in the present work in order to know the pharmacological activities and medicinal uses of corylin in the scientific fields. However, analytical techniques data of corylin have also been collected and analyzed for standardization of Psoralea corylifolia and other medicinal plants. RESULTS Scientific data analysis of research works revealed the medicinal importance of Psoralea corylifolia and its important phytoconstituents corylin in the medicine. Scientific data analysis revealed that corylin is a flavonoidal class phytochemical found to be present in the nuts of Psoralea corylifolia L. Biological importance of corylin in bone differentiation, bone growth, osteoporosis have been proven in the scientific research work. Anti-inflammatory, anti-oxidant and antitumor activity of corylin has been also mentioned in the medicine. Biological importances of corylin in hyperlipidemia, insulin resistance, atherosclerosis, hepatocellular carcinoma and neurodisorders have also been presented in this work. CONCLUSION Scientific data analysis revealed the biological importance and therapeutic potential of corylin in the medicine.