Recent advances in nano-scaffolds for tissue engineering applications: Toward natural therapeutics.

IF 8.2 2区 医学 Q1 MEDICINE, RESEARCH & EXPERIMENTAL Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology Pub Date : 2023-11-01 Epub Date: 2023-02-22 DOI:10.1002/wnan.1882
Azizeh Rahmani Del Bakhshayesh, Solmaz Saghebasl, Nahideh Asadi, Elmira Kashani, Ahmad Mehdipour, Amir Nezami Asl, Abolfazl Akbarzadeh
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引用次数: 6

Abstract

Among the promising methods for repairing or replacing tissue defects in the human body and the hottest research topics in medical science today are regenerative medicine and tissue engineering. On the other hand, nanotechnology has been expanded into different areas of regenerative medicine and tissue engineering due to its essential benefits in improving performance in various fields. Nanotechnology, a helpful strategy in tissue engineering, offers new solutions to unsolved problems. Especially considering the excellent physicochemical properties of nanoscale structures, their application in regenerative medicine has been gradually developed, and a lot of research has been conducted in this field. In this regard, various nanoscale structures, including nanofibers, nanosheets, nanofilms, nano-clays, hollow spheres, and different nanoparticles, have been developed to advance nanotechnology strategies with tissue repair goals. Here, we comprehensively review the application of the mentioned nanostructures in constructing nanocomposite scaffolds for regenerative medicine and tissue engineering. This article is categorized under: Nanotechnology Approaches to Biology > Nanoscale Systems in Biology Implantable Materials and Surgical Technologies > Nanotechnology in Tissue Repair and Replacement Diagnostic Tools > Biosensing.

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纳米支架在组织工程中的应用进展:走向自然疗法。
再生医学和组织工程是修复或替代人体组织缺陷的最有前途的方法之一,也是当今医学领域最热门的研究课题。另一方面,纳米技术已经扩展到再生医学和组织工程的不同领域,因为它在提高各个领域的性能方面具有重要的好处。纳米技术在组织工程中是一种有用的策略,为未解决的问题提供了新的解决方案。特别是考虑到纳米结构优异的物理化学性质,其在再生医学中的应用逐渐得到发展,并在该领域进行了大量的研究。在这方面,各种纳米级结构,包括纳米纤维、纳米片、纳米膜、纳米粘土、空心球和不同的纳米颗粒,已经被开发出来,以推进具有组织修复目标的纳米技术策略。本文综述了上述纳米结构在构建再生医学和组织工程纳米复合材料支架中的应用。本文分类如下:纳米技术在生物学中的应用;纳米系统在生物学中的应用;可植入材料和外科技术;纳米技术在组织修复和替代诊断工具中的应用;纳米技术在生物传感中的应用。
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来源期刊
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology NANOSCIENCE & NANOTECHNOLOGY-MEDICINE, RESEARCH & EXPERIMENTAL
CiteScore
16.60
自引率
2.30%
发文量
93
期刊介绍: Nanotechnology stands as one of the pivotal scientific domains of the twenty-first century, recognized universally for its transformative potential. Within the biomedical realm, nanotechnology finds crucial applications in nanobiotechnology and nanomedicine, highlighted as one of seven emerging research areas under the NIH Roadmap for Medical Research. The advancement of this field hinges upon collaborative efforts across diverse disciplines, including clinicians, biomedical engineers, materials scientists, applied physicists, and toxicologists. Recognizing the imperative for a high-caliber interdisciplinary review platform, WIREs Nanomedicine and Nanobiotechnology emerges to fulfill this critical need. Our topical coverage spans a wide spectrum, encompassing areas such as toxicology and regulatory issues, implantable materials and surgical technologies, diagnostic tools, nanotechnology approaches to biology, therapeutic approaches and drug discovery, and biology-inspired nanomaterials. Join us in exploring the frontiers of nanotechnology and its profound impact on biomedical research and healthcare.
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