{"title":"Improvement of oocyte quality through the SIRT signaling pathway.","authors":"Kim Cat Tuyen Vo, Yorino Sato, Kazuhiro Kawamura","doi":"10.1002/rmb2.12510","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Oocyte quality is one of the major deciding factors in female fertility competence.</p><p><strong>Methods: </strong>PubMed database was searched for reviews by using the following keyword \"oocyte quality\" AND \"Sirtuins\". The methodological quality of each literature review was assessed using the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) 2020 statement.</p><p><strong>Main findings: </strong>Oxidative stress has been recognized as the mechanism attenuating oocyte quality. Increasing evidence from animal experiments and clinical studies has confirmed the protective roles of the sirtuin family in improving oocyte quality via an antioxidant effect.</p><p><strong>Conclusion: </strong>The protective roles in the oocyte quality of the sirtuin family have been increasingly recognized.</p>","PeriodicalId":21116,"journal":{"name":"Reproductive Medicine and Biology","volume":null,"pages":null},"PeriodicalIF":2.7000,"publicationDate":"2023-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1d/4e/RMB2-22-e12510.PMC9949364.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Reproductive Medicine and Biology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/rmb2.12510","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Oocyte quality is one of the major deciding factors in female fertility competence.
Methods: PubMed database was searched for reviews by using the following keyword "oocyte quality" AND "Sirtuins". The methodological quality of each literature review was assessed using the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) 2020 statement.
Main findings: Oxidative stress has been recognized as the mechanism attenuating oocyte quality. Increasing evidence from animal experiments and clinical studies has confirmed the protective roles of the sirtuin family in improving oocyte quality via an antioxidant effect.
Conclusion: The protective roles in the oocyte quality of the sirtuin family have been increasingly recognized.
期刊介绍：
Reproductive Medicine and Biology (RMB) is the official English journal of the Japan Society for Reproductive Medicine, the Japan Society of Fertilization and Implantation, the Japan Society of Andrology, and publishes original research articles that report new findings or concepts in all aspects of reproductive phenomena in all kinds of mammals. Papers in any of the following fields will be considered: andrology, endocrinology, oncology, immunology, genetics, function of gonads and genital tracts, erectile dysfunction, gametogenesis, function of accessory sex organs, fertilization, embryogenesis, embryo manipulation, pregnancy, implantation, ontogenesis, infectious disease, contraception, etc.
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