Aortic Root Surgery in Adults: An Unsolved Problem.

Q3 Medicine AORTA Pub Date : 2023-02-01 DOI:10.1055/s-0042-1757949
Carlotta Brega, Alberto Albertini
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Abstract

Nowadays, despite the rapid advancements in interventional cardiology, open surgery still deals with aortic root diseases, to assure the best "ad hoc" treatment. In case of middle-aged adult patients, the optimal operation still represents a matter of debate. A review of the last 10-year literature was conducted, focusing on patients below 65 to 70 years of age. Because of the small sample and the heterogeneity of the papers, no metanalysis was possible. Bentall-de Bono procedure, valve sparing, and Ross operations are the surgical options currently available. The main issues in the Bentall - de Bono operation are lifelong anticoagulation therapy and cavitation in case of mechanical prosthesis implantation and structural valve degeneration in case of biological Bentall. As transcatheter procedures are currently performed as valve in valve, biological prosthesis may be preferable, if the diameter may prevent postoperative high gradients. Conservative techniques, such as remodeling and reimplantation, preferred in the young, guarantee physiologic aortic root dynamics and impose surgical analysis of the aortic root structures to get a durable result. The Ross operation, which shows excellent performance, involves autologous pulmonary valve implantation and is performed only in experienced and high-volume centers. Due to its technical difficulty, it requires a steep learning curve and presents some limitations in specific aortic valve diseases. All three have advantages and downsides, and no ideal solution has still been reported.

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成人主动脉根部手术:一个未解决的问题。
如今,尽管介入心脏病学发展迅速,但开放手术仍然涉及主动脉根部疾病,以确保最佳的“特设”治疗。对于中年患者,最佳的手术方式仍然是一个有争议的问题。对过去10年的文献进行了回顾,重点是65至70岁以下的患者。由于样本量小和论文的异质性,不可能进行meta分析。Bentall-de Bono手术、保留瓣膜和Ross手术是目前可用的手术选择。本特尔-德博诺手术的主要问题是终身抗凝治疗和机械性假体植入时的空化,以及生物本特尔手术时的结构瓣膜退变。由于目前经导管手术是瓣膜中瓣膜,如果直径可以防止术后高梯度,生物假体可能是首选。保守的技术,如重塑和再植,在年轻人中首选,保证了生理的主动脉根动力学,并要求对主动脉根结构进行手术分析,以获得持久的结果。Ross手术表现优异,涉及自体肺动脉瓣植入,仅在经验丰富且容量大的中心进行。由于技术上的困难,它需要一个陡峭的学习曲线,并且在特定的主动脉瓣疾病中存在一些局限性。这三种方法各有优缺点,目前还没有理想的解决方案。
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来源期刊
AORTA
AORTA Medicine-Surgery
CiteScore
1.00
自引率
0.00%
发文量
119
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