Higher milk consumption is not associated with fracture risk reduction: systematic review and meta-analysis.

Q3 Medicine Folia medica Cracoviensia Pub Date : 2022-12-29 DOI:10.24425/ fmc.2022.144088

Grzegorz Goncerz, Patrycja Kojm, Sylwia Skocelas, Krzysztof Więckowski, Tomasz Gallina, Paulina Pietrzyk, Sebastian Goncerz

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Abstract

Introduction: Osteoporosis affects over 200 million people worldwide causing nearly 9 million fractures annually, with more than half in America and Europe.

Objectives: This meta-analysis was conducted to investigate whether low milk intake is associated with an increased risk of fractures by summarizing all the available evidence.

Methods: Relevant studies were identified by searching the PubMed and EMBASE databases up to June 2020. The pooled relative risks with 95% confidence intervals were calculated.

Results: In a meta-regression analysis of 20 included studies (11 cohort and 9 case-control studies), a higher milk intake was not associated with a reduction in the total fracture risk in both sexes (OR 0.95, 95% CI: 0.84- 1.08), either in cohort (OR 0.91; 95% CI: 0.79-1.05) or case-control studies (OR 1.09; 95% CI: 0.82-1.44), as well as separately in men (OR 0.87; 95% CI: 0.71-1.07) and women (OR 0.95; 95% CI: 0.80-1.13).

Conclusion: Higher milk consumption is not associated with fracture risk reduction and should not be recommended for fracture prevention.

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多喝牛奶与降低骨折风险无关：系统综述和荟萃分析。

导言：骨质疏松症影响着全球 2 亿多人，每年造成近 900 万例骨折，其中一半以上发生在美国和欧洲：本荟萃分析旨在通过总结所有可用证据，研究牛奶摄入量低是否与骨折风险增加有关：方法：通过检索截至 2020 年 6 月的 PubMed 和 EMBASE 数据库，确定了相关研究。结果：在一项荟萃回归分析（meta-regression analysis）中，研究人员发现，牛奶与骨折的发生有关：结果：在对 20 项纳入研究（11 项队列研究和 9 项病例对照研究）进行的元回归分析中，牛奶摄入量增加与男女总骨折风险降低无关（OR 0.95，95% CI：0.84- 1.08），无论是队列研究（OR 0.91；95% CI：0.79-1.05）还是病例对照研究（OR 1.09；95% CI：0.82-1.44），以及男性（OR 0.87；95% CI：0.71-1.07）和女性（OR 0.95；95% CI：0.80-1.13）均是如此：结论：多喝牛奶与降低骨折风险无关，因此不应推荐用于预防骨折。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Folia medica Cracoviensia Medicine-Medicine (all)

CiteScore

1.20

自引率

0.00%

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