Analysis on Early and Late Operation Results and Risk Factors of Elderly Acute Type-A Aortic Dissection.

IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Neuro endocrinology letters Pub Date : 2022-12-29
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Abstract

Objective: To explore the early and late operation results and risk factors of elderly acute type-A aortic dissection.

Methods: The regression analysis was conducted on the data of patients diagnosed with acute type-A aortic dissection in our hospital from January 2018 to January 2020, and a total of 98 patients aged over 70 years were included in the study. The patients were listed into the early operation group (a total of 51 patients operated within 3 days after admission) and the late operation group (a total of 47 patients operated within 10 days after admission) according to the time of operation. The operation results, postoperative complications and death were compared between the two groups, and the prognosis risk factors were analyzed through Logistic multi-factor regression.

Results: The operative time, aortic obstruction time and extracorporeal circulation time of the late operation group were all higher than those in the early operation group (p <0.05). The postoperative complications and mortality in the late operation group (12.77%) were higher than those in the early operation group (3.92%) (p < 0.05). The Logistic multi-factor regression showed that late operation (p=0.005, OR=4.213, 95% CI=1.567~11.201), postoperative acute renal insufficiency (p=0.028, OR=3.281, 95% CI=0.937~10.283), and postoperative pulmonary infection (p=0.033, OR=1.421, 95% CI=0.417~8.329) were risk factors affecting postoperative mortality (p <0.05).

Conclusion: The early operation can effectively reduce the postoperative complications of elderly acute type-A aortic dissection, so early operation should be performed according to the conditions of patients and hospital.

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老年急性a型主动脉夹层早、晚期手术效果及危险因素分析。
目的:探讨老年急性a型主动脉夹层早、晚期手术效果及危险因素。方法:对我院2018年1月至2020年1月诊断为急性a型主动脉夹层的患者资料进行回归分析,共纳入98例70岁以上患者。根据手术时间分为早期手术组(入院后3天内手术51例)和晚期手术组(入院后10天内手术47例)。比较两组手术效果、术后并发症及死亡情况,采用Logistic多因素回归分析预后危险因素。结果:晚期手术组的手术时间、主动脉阻塞时间、体外循环时间均高于早期手术组(p)。结论:早期手术可有效减少老年急性a型主动脉夹层术后并发症,应根据患者及医院情况及早手术。
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来源期刊
Neuro endocrinology letters
Neuro endocrinology letters 医学-内分泌学与代谢
CiteScore
1.00
自引率
14.30%
发文量
24
审稿时长
6 months
期刊介绍: Neuroendocrinology Letters is an international, peer-reviewed interdisciplinary journal covering the fields of Neuroendocrinology, Neuroscience, Neurophysiology, Neuropsychopharmacology, Psycho­neu­ro­immunology, Reproductive Medicine, Chro­no­biology, Human Ethology and re­lated fields for RAPID publication of Original Papers, Review Articles, State-of-the-art, Clinical Reports and other contributions from all the fields covered by Neuroendocrinology Letters. Papers from both basic research (methodology, molecular and cellular biology, anatomy, histology, biology, embryology, teratology, normal and pathological physiology, biophysics, pharmacology, pathology and experimental pathology, biochemistry, neurochemistry, enzymology, chronobiology, receptor studies, endocrinology, immunology and neuroimmunology, animal phy­siology, animal breeding and ethology, human ethology, psychology and others) and from clinical research (neurology, psychiatry and child psychiatry, obstetrics and gynecology, pediatrics, endocrinology, immunology, cardiovascular studies, internal medicine, oncology and others) will be considered. The Journal publishes Original papers and Review Articles. Brief reports, Special Communications, proved they are based on adequate experimental evidence, Clinical Studies, Case Reports, Commentaries, Discussions, Letters to the Editor (correspondence column), Book Reviews, Congress Reports and other categories of articles (philosophy, art, social issues, medical and health policies, biomedical history, etc.) will be taken under consideration.
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