Relief of Central Poststroke Pain Affecting Both the Arm and Leg on One Side by Double-independent Dual-lead Spinal Cord Stimulation Using Fast-acting Subperception Therapy Stimulation: A Case Report.

Takafumi Tanei, Satoshi Maesawa, Yusuke Nishimura, Yoshitaka Nagashima, Tomotaka Ishizaki, Manabu Mutoh, Yoshiki Ito, Ryuta Saito
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Abstract

Central poststroke pain is a chronic, intractable, central neuropathic pain. Spinal cord stimulation is a neuromodulation therapy for chronic neuropathic pain. The conventional stimulation method induces a sense of paresthesia. Fast-acting subperception therapy is one of the latest new stimulation methods without paresthesia. A case of achieving pain relief of central poststroke pain affecting both the arm and leg on one side by double-independent dual-lead spinal cord stimulation using fast-acting subperception therapy stimulation is presented. A 67-year-old woman had central poststroke pain due to a right thalamic hemorrhage. The numerical rating scale scores of the left arm and leg were 6 and 7, respectively. Using dual-lead stimulation at the Th 9-11 levels, a spinal cord stimulation trial was performed. Fast-acting subperception therapy stimulation achieved pain reduction in the left leg from 7 to 3. Therefore, a pulse generator was implanted, and the pain relief continued for 6 months. Then, two additional leads were implanted at the C 3-5 levels, and pain in the arm decreased from 6 to 4. Independent setting and adjustments of the dual-lead stimulation were required because the thresholds of paresthesia perception were significantly different. To achieve pain relief in both the arm and leg, double-independent dual-lead stimulation placed at cervical and thoracic levels is an effective treatment. Fast-acting subperception therapy stimulation may be effective for central poststroke pain, especially in cases where the paresthesia is perceived as uncomfortable or the conventional stimulation itself is ineffective.

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双独立双导联脊髓快速亚知觉治疗缓解单侧手臂和腿部中枢性脑卒中后疼痛1例
中枢性脑卒中后疼痛是一种慢性、难治性中枢神经性疼痛。脊髓刺激是一种治疗慢性神经性疼痛的神经调节疗法。传统的刺激方法会引起感觉异常。速效亚知觉治疗是一种新的无感觉异常的刺激方法。本文报道了一种采用双独立双导脊髓快速亚知觉治疗刺激的方法,实现单侧手臂和腿部中枢性脑卒中后疼痛缓解的病例。一位67岁的女性因右丘脑出血而出现中枢性中风后疼痛。左臂和左腿的数值评定量表得分分别为6分和7分。采用双导联刺激th9 -11水平,进行脊髓刺激试验。速效亚知觉治疗刺激使左腿疼痛从7减轻到3。因此,植入脉冲发生器,疼痛缓解持续6个月。然后,在c3 -5水平植入两个额外的导线,手臂疼痛从6减少到4。双导联刺激需要独立设置和调整,因为感觉异常知觉阈值有显著差异。为了缓解手臂和腿部的疼痛,在颈椎和胸椎水平放置双独立双导联刺激是一种有效的治疗方法。速效亚知觉治疗刺激可能对中枢性卒中后疼痛有效,特别是在感觉异常被认为不舒服或常规刺激本身无效的情况下。
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