Bilateral Ureterohydronephrosis after Intestinal Pseudo-obstruction in a Patient with Systemic Lupus Erythematosus.

Abstract

A 22-year-old female presented with an 18-month history of frequent urination and urinary urgency. Her physical examination showed a cushingoid appearance and no ob-vious tenderness or palpable mass in the renal and ureteral walking areas. Her past medical history was notable for systemic lupus erythematosus (SLE) and lupus nephri-tis diagnosed 10 years ago, and SLE-associated intestinal pseudo-obstruction (IPO) diagnosed 3 years ago. Her IPO achieved remission after treatment with intravenous methylprednisolone and cyclophosphamide (cumulative dose 5 g). Her methylprednisolone was tapered to 8 mg/day, when she suffered from frequent urination and urinary urgency. Laboratory tests showed a urinary albumin level of 0.3 g/L and a serum creatinine