Louis Pasteur, molecular dissymmetry, therapeutic chemistry and neuropharmacology.

IF 0.7 4区 生物学 Q4 BIOLOGY Comptes Rendus Biologies Pub Date : 2022-11-10 DOI:10.5802/crbiol.81
Jean-Pierre Changeux
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Abstract

Louis Pasteur is celebrated as the founding father of microbiology. But he was a chemist by training and discovered molecular dissymmetry experimentally. All his life, his constant preoccupation will be to apply the method and strategies of the fundamental sciences to living processes, "from the molecule to the brain". His fundamental aim will be, beyond the biology of microbes, the chemistry of life, a disposition which signs the originality of his work. More unexpectedly, Pasteur was at the origin of therapeutic chemistry-which his successors, and especially Daniel Bovet, brilliantly illustrated at the Pasteur Institute and which they would pursue with the pharmacology of the nervous system or "neuropharmacology".

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路易斯·巴斯德,分子不对称,治疗化学和神经药理学。
路易斯·巴斯德被誉为微生物学之父。但他是一名经过训练的化学家,通过实验发现了分子不对称。在他的一生中,他始终专注于将基础科学的方法和策略应用于生命过程,“从分子到大脑”。他的基本目标将超越微生物的生物学,是生命的化学,一种标志着他的工作独创性的气质。更令人意想不到的是,巴斯德是治疗化学的鼻祖——他的继任者,尤其是丹尼尔·博韦,在巴斯德研究所出色地阐释了这一点,他们将继续研究神经系统药理学或“神经药理学”。
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来源期刊
Comptes Rendus Biologies
Comptes Rendus Biologies 生物-生物学
CiteScore
2.40
自引率
0.00%
发文量
22
审稿时长
3 months
期刊介绍: The Comptes rendus Biologies publish monthly communications dealing with all biological and medical research fields (biological modelling, development and reproduction biology, cell biology, biochemistry, neurosciences, immunology, pharmacology, ecology, etc.). Articles are preferably written in English. Articles in French with an abstract in English are accepted.
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