{"title":"The effect of miotics on the intraocular pressure of conscious owl monkeys.","authors":"J W Lamble, A P Lamble","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The intraocular pressure of conscious, unsedated owl monkeys (Aotus trivirgatus) was measured with an applanation tonometer. Untreated eyes of the conscious animals were found to have higher values than those reported for owl monkeys anesthetized with pentobarbitone. Locally applied pilocarpine, carbachol, and oxotremorine gave concentration-related reduction in pressure, oxotremorine being the most potent and having longer duration of effect than the other compounds. Slight reductions were also observed with aceclidine and R. S. 86. These results are discussed in relation to the effects of miotics in man.</p>","PeriodicalId":14844,"journal":{"name":"Investigative ophthalmology","volume":"15 10","pages":"848-51"},"PeriodicalIF":0.0000,"publicationDate":"1976-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Investigative ophthalmology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The intraocular pressure of conscious, unsedated owl monkeys (Aotus trivirgatus) was measured with an applanation tonometer. Untreated eyes of the conscious animals were found to have higher values than those reported for owl monkeys anesthetized with pentobarbitone. Locally applied pilocarpine, carbachol, and oxotremorine gave concentration-related reduction in pressure, oxotremorine being the most potent and having longer duration of effect than the other compounds. Slight reductions were also observed with aceclidine and R. S. 86. These results are discussed in relation to the effects of miotics in man.
用眼压计测量清醒、未镇静的猫头鹰猴(Aotus trivirgatus)的眼压。未处理的清醒动物的眼睛比用戊巴比酮麻醉的猫头鹰猴子的眼睛值更高。局部应用匹罗卡品、卡巴醇和氧tremorine可使压力随浓度降低，其中氧tremorine是最有效的，并且比其他化合物的作用持续时间更长。用aceclidine和R. S. 86也观察到轻微的减少。这些结果讨论了拟态对人的影响。
分享
京公网安备 11010802042870号
京ICP备2023020795号-1
求助内容：
应助结果提醒方式：
扫码关注我们
