Experiments for the production of graft-versus-host reaction in adult and infantile mice by means of human immunocompetent cells.

Annales immunologiae Hungaricae Pub Date : 1975-01-01
L Réthy, E Osz
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Abstract

By administering anti-mouse ATS five times to random-bred Swiss albino mice weighing 16-18 and 10-11 g respectively, the authors have tried to produce immunological depression of such a degree which would allow living human leukocytes to cause GVH reaction. On the basis of the results it may be stated that with the serum dosage and manner of treatment applied, the human graft was not able to act against the recipient organism and to produce differences in body weight.

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利用人免疫活性细胞在成年和幼鼠体内产生移植物抗宿主反应的实验。
通过给随机饲养的体重分别为16-18克和10-11克的瑞士白化小鼠注射5次抗小鼠ATS,作者试图产生一定程度的免疫抑制,使活的人类白细胞能够引起GVH反应。根据这些结果可以说明,在不同的血清剂量和处理方式下,人体移植物不能对受体机体起作用,也不能产生体重差异。
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Immunodiffusion study on group-specific antigen of MC-29 chicken hepatoma. Studies of pre- and postimmunization antibodies of sheep. Synthesis and studies of transferrin. Potency of PPD preparations derived from M. tuberculosis and M. bovis. Immune responsiveness of patients with autoimmune diseases and immunodeficiency.
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