Enzyme changes after coronary angiography.

A Weikl, M Hubmann, O E Durst, E Lang
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引用次数: 0

Abstract

The enzymatic response to contrast media after coronary angiography was observed in 24 patients. The enzymes studied were glutamic oxaloacetic transaminase (SGOT), glutamic pyruvic transaminase (SGPT), lactic dehydrogenase (LDH), alpha-hydroxybutyrate dehydrogenase (alpha-HBDH), gamma-glutamyl transferase (gamma-GT), creatine phosphokinase (CPK), and the myocardial-specific isoenzyme of CPK (CK-MB). Angiography produced no significant elevations in SGOT, SGPT, alpha-HBDH, LDH, or CK-MB activities; gamma-GT increased up to the twelfth hour. High levels of CPK and CK-MB observed in one patient were found to be products of a thymus carcinoma. In vitro examinations also showed that concentrations of contrast media used in coronary angiography do not inhibit gamma-GT, LDH, and CPK activities.

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冠状动脉造影后的酶变化。
观察24例冠状动脉造影后造影剂的酶促反应。所研究的酶有谷草酰转氨酶(SGOT)、谷丙转氨酶(SGPT)、乳酸脱氢酶(LDH)、α -羟丁酸脱氢酶(α - hbdh)、γ -谷氨酰基转移酶(γ - gt)、肌酸磷酸激酶(CPK)和心肌特异性CPK同工酶(CK-MB)。血管造影未显示SGOT、SGPT、α - hbdh、LDH或CK-MB活性显著升高;γ - gt增加到第十二小时。在一名患者中观察到高水平的CPK和CK-MB被发现是胸腺癌的产物。体外检查也显示冠脉造影中使用的造影剂浓度不会抑制γ - gt、LDH和CPK活性。
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