{"title":"Urinary metabolites from gamma- and beta-BHC in the mouse: chlorophenol conjugates.","authors":"N Kurihara","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Metabolites produced from gamma- and beta-BHC in the mouse urine were purified and characterized. Most metabolites from both isomers were not extractable by non-polar organic solvents and were conjugates such as sulfates and glucuronides. After hydrolysis with an appropriate enzyme, the conjugates gave chlorophenols, among which 2,4,6-trichlorophenol existed most abundantly (total, about 25% in the urine metabolites). 2,4-Dichlorophenol also constituted a significant portion.</p>","PeriodicalId":75827,"journal":{"name":"Environmental quality and safety","volume":"4 ","pages":"56-73"},"PeriodicalIF":0.0000,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Environmental quality and safety","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Metabolites produced from gamma- and beta-BHC in the mouse urine were purified and characterized. Most metabolites from both isomers were not extractable by non-polar organic solvents and were conjugates such as sulfates and glucuronides. After hydrolysis with an appropriate enzyme, the conjugates gave chlorophenols, among which 2,4,6-trichlorophenol existed most abundantly (total, about 25% in the urine metabolites). 2,4-Dichlorophenol also constituted a significant portion.
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