[2,4-dinitro-(pyrimidine-2-yl) thiophenol, a new drug with antimitotic properties].

R Bassleer, F de Paermentier, A Lepoint, M P Lhoest-Gauthier, J C Jamoulle, C L Lapière
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引用次数: 0

Abstract

A new thiopyrimidine derivative has been synthesized. It can inhibit cell multiplication in Chick embryo fibroblasts, in Mouse Ehrlich ascites tumor cells and in Rat hepatoma cells (line Rueber) cultivated in vitro.

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[2,4-二硝基-(嘧啶-2-基)噻吩,一种具有抗有丝分裂特性的新药]。
合成了一种新的硫代嘧啶衍生物。对体外培养的鸡胚成纤维细胞、小鼠埃利希腹水肿瘤细胞和大鼠肝癌细胞均有抑制作用。
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