[Serum iodothyronine concentrations and properties of mitochondria phosphorylative oxidations in old rats].

S Naltchayan, J Bouhnik, R Michel
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Abstract

Serum concentrations of T4 and T3 in 2 year-old Rats were decreased by about 30% compared to 2 month-old animals, but rT3 was similar. Activities of old Rats' liver mitochondria were near those of young thyroidectomized animals. Low circulating T3 partly explains metabolic changes observed during senescence.

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[老年大鼠血清碘甲状腺原氨酸浓度和线粒体磷酸化氧化的性质]。
与2月龄大鼠相比,2岁大鼠血清T4和T3浓度下降约30%,但rT3相似。老龄大鼠肝脏线粒体活性与去甲状腺幼龄大鼠相近。低循环T3部分解释了衰老过程中观察到的代谢变化。
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