{"title":"[Group-allergic reaction spectrum and sensitization potency of benzylisothiocyanate].","authors":"G Richter, U Heidelbach, I Heidenbluth, H Kadner","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Allergenicity of benzylisothiocyanate and group-allergic cross reactions. Comparative patch-test series made in pateints suffering from contact dermatitis induced by Sulbentin (Dibenzthion)-antimycotics and in guinea pigs, experimentally sensitized to benzylisothiocyanate (BITC), showed: BITC is a potent contact sensitizer and the real hapten in cases of Sulbentin-allergy. Of special importance in this molecule is the benzyl-group. Neither 4,4-diphenylmethandiisocyanate and isophorondiisocyanate (substances used in polyurethane production) nor the closely related methylisothiocyanate (decomposition product of some potato-selecting agents) produced any groupallergic cross reactions in the above-mentioned patients and guinea pigs.</p>","PeriodicalId":8796,"journal":{"name":"Berufs-Dermatosen","volume":"24 6","pages":"147-51"},"PeriodicalIF":0.0000,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Berufs-Dermatosen","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Allergenicity of benzylisothiocyanate and group-allergic cross reactions. Comparative patch-test series made in pateints suffering from contact dermatitis induced by Sulbentin (Dibenzthion)-antimycotics and in guinea pigs, experimentally sensitized to benzylisothiocyanate (BITC), showed: BITC is a potent contact sensitizer and the real hapten in cases of Sulbentin-allergy. Of special importance in this molecule is the benzyl-group. Neither 4,4-diphenylmethandiisocyanate and isophorondiisocyanate (substances used in polyurethane production) nor the closely related methylisothiocyanate (decomposition product of some potato-selecting agents) produced any groupallergic cross reactions in the above-mentioned patients and guinea pigs.
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