Enzymatic changes in lung tissue of asbestotic guinea pigs.

J Singh, M U Beg, P N Viswanathan, S H Zaidi
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Abstract

The changes in the activities of some mitochondrial and soluble enzymes in the lungs of guinea pig, caused by three varieties of asbestos dust 120 days after intratracheal injection, were studied. Marked increase was observed in mitochondrial cytochrome oxidase, diaphorase and malic dehydrogenase. Among the soluble enzymes, lactic dehydrogenase showed the maximum variation.

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石棉豚鼠肺组织中酶的变化。
本文研究了三种石棉粉尘对豚鼠气管内注射120 d后肺组织中部分线粒体和可溶性酶活性的影响。线粒体细胞色素氧化酶、二磷酸腺苷酶和苹果脱氢酶明显升高。可溶性酶中,乳酸脱氢酶变化最大。
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