Viral infections.

J A Dudgeon
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Abstract

Although rubella is the only virus which can be regarded in the strict sense of the term a teratogen, there is no convincing evidence that other viruses can cause fetal damage of varying severity. The risk to the fetus appears to depend on the nature of the infectious agent, the maternal immune status and the gestational age when infection takes place. The possibility that subclinical maternal infections may cause damage must not be overlooked. As some of the viruses referred to can cause damage after the period of organogenesis, the use of the term 'teratogenic efect' in relation to viral infections is considered to be inappropriate.

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病毒感染。
虽然风疹是唯一一种严格意义上可被视为致畸原的病毒,但没有令人信服的证据表明其他病毒可造成不同程度的胎儿损害。对胎儿的风险似乎取决于感染原的性质、母亲的免疫状况和感染发生时的胎龄。亚临床母体感染可能造成损害的可能性不容忽视。由于所提到的某些病毒可在器官发生期后造成损害,因此在涉及病毒感染时使用“致畸效应”一词被认为是不恰当的。
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