A comparison of continuous positive airway pressure initiation techniques in the treatment of obstructive sleep apnoea/hypopnoea syndrome in adults

Maxwell Stanley Renna
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Abstract

Introduction: This project assesses the differences between CPAP usage, a year after initiation, when patients were introduced to therapy via inpatient respiratory studies, outpatient auto-titration studies or a combination of the two. Methods: The retrospective review of 98 CPAP patients’ usage data was collected and statistically analysed using ANOVA tests, Chi-squared and Kruskal Wallace testing. Results: The findings showed a small clinically significant difference but no statistically significant differences in usage across the three groups (p>0.05). Combining initiation techniques improved yearly CPAP usage by up to 365 hours. The difference between RESP and APAP average usage was 90 hours a year. No statistically significant difference in usage between the three groups was seen. The APAP pathway is the most cost-effective and significantly reduces the time taken to get on to CPAP treatment. Demographic variables are not found to predict nightly usage. All patients increased in weight over the year. Conclusion: The results demonstrate higher levels of usage when combining initiation techniques, indicating initiation with high levels of interaction with healthcare professionals is beneficial. Significant weight gain across all groups poses the moral question of whether CPAP should be issued prior to initial weight loss attempts.
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持续气道正压启动技术治疗成人阻塞性睡眠呼吸暂停/低通气综合征的比较
本项目评估了CPAP使用一年后的差异,当患者通过住院呼吸研究、门诊自动滴定研究或两者结合进行治疗时。方法:回顾性分析98例CPAP患者的使用资料,采用方差分析、卡方检验和Kruskal Wallace检验进行统计学分析。结果:三组患者的用药情况差异无统计学意义(p < 0.05),但临床差异较小(p < 0.05)。联合启动技术可使每年的CPAP使用率提高365小时。RESP和APAP的平均使用时间相差为每年90小时。三组之间的使用没有统计学上的显著差异。APAP途径是最具成本效益的,可显著减少进行CPAP治疗所需的时间。没有发现人口统计学变量可以预测每晚的使用量。所有患者的体重在这一年中都有所增加。结论:结果表明,当结合起始技术时,使用率更高,表明起始与医疗专业人员的高水平互动是有益的。所有组的体重明显增加提出了一个道德问题,即是否应该在最初的减肥尝试之前进行CPAP。
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