{"title":"Translational regulatory mechanisms in neoplasia in vivo.","authors":"H C Pitot","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>It is clear that regulation of genetic expression of cells need not involve alterations of the basic DNA structure. Between the production of messenger RNA and enzyme degradation there are a number of steps, any of which can be modulated by hormones and other factors to yield cellular abnormalities associated with malignancy. It is important to identify the exact step at which a carcinogen operates and to discover how this alteration is transmitted to the progeny of malignant cells.</p>","PeriodicalId":75448,"journal":{"name":"Advances in pathobiology","volume":"2 ","pages":"29-33"},"PeriodicalIF":0.0000,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in pathobiology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
It is clear that regulation of genetic expression of cells need not involve alterations of the basic DNA structure. Between the production of messenger RNA and enzyme degradation there are a number of steps, any of which can be modulated by hormones and other factors to yield cellular abnormalities associated with malignancy. It is important to identify the exact step at which a carcinogen operates and to discover how this alteration is transmitted to the progeny of malignant cells.
分享
京公网安备 11010802042870号
京ICP备2023020795号-1
求助内容：
应助结果提醒方式：
扫码关注我们
