Diagnostic Value of the Laboratory Markers of Acute Cytomegalovirus Infection in Patients With Systemic Lupus Erythematosus

Abstract

and lymphopenia in SLE patients can correctly predict the presence of acute CMV infection at 67.50 %. Conclusions. Anemia, leukopenia, lymphopenia, increase in γ-globulin content, increase in antibody titer to two-helical deoxyribonucleic acid, decrease in complement rate are laboratory markers of acute cytomegalovirus infection in patients with systemic lupus erythematosus. A constellation of indicators was found to have the highest sensitivity, specificity, and association coefficient with the presence of acute cytomegalovirus infection, namely: leukopenia and lymphopenia. Considering the presence of these indicators in patients with systemic lupus erythematosus will allow to form groups of risk of acute cytomegalovirus infection, and therefore to examine the patient and to choose the right tactics of treatment.