Seguridad de los tratamientos antirreumáticos en la paciente gestante

Inmaculada Chalmeta Verdejo
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Abstract

In recent years, there has been a change in attitude concerning the use of antirheumatic drugs during pregnancy. Ideally, they should be suspended before pregnancy, however, in certain cases it may be necessary to use them to protect mother's health and ensure a correct pregnancy delivery. The most commonly used antirheumatic drugs in pregnancy have been reviewed. Results show that some of them can be taken during pregnancy with a low risk of toxicity, but others should not be administered in this period because of fetal toxicity. Regarding biological therapies in rheumatic diseases, recent studies show that TNF blockers could be continued during the first months of pregnancy.

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孕妇抗风湿治疗的安全性
近年来,人们对怀孕期间使用抗风湿药物的态度发生了变化。理想情况下,它们应该在怀孕前停用,但是,在某些情况下,可能有必要使用它们来保护母亲的健康并确保正确的妊娠分娩。本文综述了妊娠期最常用的抗风湿药物。结果表明,其中一些药物可以在怀孕期间服用,毒性风险低,但其他药物由于胎儿毒性而不应在此期间使用。关于风湿病的生物治疗,最近的研究表明,TNF阻滞剂可以在怀孕的头几个月继续使用。
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