Non-Invasive Heat-Induced Numerous Tissue Ablation Simulation in a Medical Environment Using Different Focal Length High Intensity Focused Ultrasound Apparatus

Anika Tun Naziba, Mohammad Nasir Uddin
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Abstract

In the field of biomedical, HIFU is a non-invasive therapeutic method that employs non-ionizing acoustic waves to increase the temperature. According to its high efficiency and cheap cost, it has been the main focus of this research. The key stages of this tumor ablation include mechanical and thermal effects. Simulations on tissue ablation with HIFU were implemented in this research to investigate how multiple tissue ablation works and how to enhance tumor ablation while avoiding injury to surrounding healthy tissue by altering the optimal intensity, power, focal length and lens radius of curvature. In order to find the optimal features of the proposed model, this analysis employs clinical applications. Numerous soft and hard tissues from the human body were chosen for this analysis. At a specified acoustic power and exposure period, each tissues optimal frequency (1.6 MHz to 3.5 MHz) and power (120 W to 140 W) were obtained for effective tissue ablation. This research performed all computations by changing the focal length from 55 mm to 65 mm. The outcomes of this therapy might require several weeks to comfortably remove tumor. This optimum result indicates that HIFU tumor ablation procedure has a high probability of success.
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利用不同焦距高强度聚焦超声仪模拟医疗环境下非侵入性热诱导大量组织消融
在生物医学领域,HIFU是一种利用非电离声波来提高温度的非侵入性治疗方法。由于其效率高、成本低,一直是本课题研究的重点。肿瘤消融的关键阶段包括机械效应和热效应。本研究对HIFU进行了组织消融模拟,探讨了多重组织消融的工作原理,以及如何通过改变最佳强度、功率、焦距和透镜曲率半径来增强肿瘤消融,同时避免损伤周围健康组织。为了找到所提出的模型的最佳特征,该分析采用临床应用。我们从人体中选取了许多软硬组织进行分析。在指定的声功率和暴露时间下,获得各组织的最佳频率(1.6 MHz ~ 3.5 MHz)和功率(120 W ~ 140 W),以实现有效的组织消融。本研究通过将焦距从55 mm更改为65 mm进行所有计算。这种治疗的结果可能需要几个星期才能舒适地切除肿瘤。这一最佳结果表明HIFU肿瘤消融手术有很高的成功率。
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