The behaviour of collagen peptidase in the serum of different dermatoses.

Archiv fur dermatologische Forschung Pub Date : 1975-01-01
G W Korting, B Morsches
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Abstract

In 150 patients with different dermatoses and 15 controls the activity of collagen peptidase in serum was determined. No relation to specific skin diseases was found. Negative findings were also observed in the group of collagenoses: only 4 of 14 patients with progressive systemic sclerosis showed an increase of this enzyme activity. These negative results seem noteworthy because it thus is demonstrated that alterations of collagen structure are not necessaryly associated with alterations of collagen peptidase activity.

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不同皮肤病患者血清中胶原肽酶的行为。
测定了150例不同皮肤病患者和15例正常人血清中胶原肽酶的活性。未发现与特定皮肤病有关。在胶原蛋白组中也观察到阴性结果:14例进行性系统性硬化症患者中只有4例显示该酶活性增加。这些阴性结果似乎值得注意,因为这表明胶原结构的改变不一定与胶原肽酶活性的改变有关。
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