Serum Low-Density Lipoprotein Levels Predict Mid-Term Outcomes of Diabetic Patients After Off-Pump Coronary Artery Bypass Surgery

Abstract

disorders, such as higher low-density lipoprotein cholesterol（LDL─C） levels and diabetes mellitus are associated with an increased risk of adverse events in the secondary prevention of coronary artery disease. These metabolic disorders are also associated with adverse events after coronary artery bypass surgery. However, few reports describe the relationship between postoperative outcomes and preoperative serum levels of mediators including levels of fasting blood sugar （FBS）, hemoglobin A1c（HbA1c） and LDL─C. This study assesses the impact of metabolic makers, including LDL─C, on mid-term outcomes of patients with diabetes after off-pump coronary artery bypass surgery. Patients ：We enrolled 350 diabetic patients who underwent isolated off-pump coronary artery bypass surgery at our institu-tion between 2003 and 2007. ：Predictors of all-cause death, cardiac death, and cardiac and cerebrovascular events（MACCE） the Cox proportional-hazards adjusted for LDL─C, FBS and other risk factors at