Bone Marrow Transplant and Bangladesh Perspective

Abstract

Availability of donors is the major concern for allogeneic SCT in which success mostly depends. Full matched HLA siblings are the most preferred donors but roughly it matches in around 30% cases. For the remaining majority cases we must depend on alternative sources like currently popular haplo-identical donors, cord blood or unrelated donors. Worldwide leading donor registries are: Australasian Bone Marrow Transplant Recipient Registry (ABMTRR), Centre for International Blood and Marrow Transplant Research (CIBMTR), the Austrian Registry (ASCTR), the Czech BMT Registry, the French Registry (SFGM), the German Registry (DRST), the Italian Registry (GITMO), the Dutch Registry (HOVON), the Spanish BMT Registry (GETH), the Swiss Registry (SBST), the Turkish BMT Registry and the British Registry (BSBMT) and Eurocord1. To arrange a cord unit or unrelated donor from these registries is exceedingly difficult in terms of logistics and costly as well. To overcome this obstacle, we need to establish a national marrow registry through which many donors could be available.