Bioceramics: From Clinic to Concept

Bryan J. Mc Entire
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Abstract

It’s been over 25 years since Professor Larry Hench published his seminal article entitled “Bioceramics: From Concept to Clinic”[1] and more than 40 years since he first reported the peculiar bioactive properties of glass compositions within the Na2O-CaO-P2O5-SiO2 quaternary system [2]. Curiously, the investigative ideas which led him to develop Bioglass® did not have their origin in the laboratory. They were born from the clinical need to heal the horrible wounds incurred by servicemen returning from the Vietnam War. Indeed, after a conversation with a ranking army officer, his work began under a simple hypothesis:
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生物陶瓷:从临床到概念
25年前,Larry Hench教授发表了他的开创性文章《生物陶瓷:从概念到临床》[1],40多年前,他首次报道了na20 - cao - p2o5 - sio2季系玻璃组分的特殊生物活性[2]。奇怪的是,导致他开发生物玻璃®的调查想法并非起源于实验室。它们的诞生是出于医治从越南战争归来的军人所受的可怕创伤的临床需要。事实上,在与一名高级军官交谈后,他的工作开始于一个简单的假设:
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