Cognitive Remediation of Working Memory Deficits in Patients with Schizophrenic Disorder

Tulika Ghosh, K. S. Sengar, A. Singh
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Abstract

Background: The present study focuses upon the effects of cognitive remediation programme upon the working memory deficits of the patients with schizophrenic disorder. Schizophrenia is a chronic, severe and debilitating psychiatric illness. It is often described in terms of positive and negative symptoms. The working memory deficits are considered a cardinal cognitive feature of schizophrenia. Methods: Five patients admitted in Ranchi Institute of NeuroPsychiatry and Allied Sciences (RINPAS), Ranchi, India in the age range of 20 to 40 years of male sex, meeting the ICD-10 DCR criteria of schizophrenia with minimum education of 12 years were taken for the study, following purposive sampling technique. A self developed socio-demographic and clinical data sheet was used to assess the socio-demographic correlates, the Positive and Negative Symptom Scale developed was used for assessing the psychotic symptoms, The Wisconsin Card Sorting Test and the Stroop test was used for assessing the executive functions and the Letter-Number Sequencing and Spatial Span Subtests taken from the Wechsler Memory ScaleIII were used for assessing the working memory of the subjects included in the study. Then a cognitive remediation programme was given to them for a period of three months after which the tests were readministered to see the effects of the intervention programme. Results: The patients suffering from schizophrenia show improved working memory ability after the cognitive remediation programme. Conclusion: Cognitive remediation programme has a positive effect upon the executive functioning,specially working memory of the patients suffering from schizophrenic disorder.
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精神分裂症患者工作记忆缺陷的认知修复
背景:本研究主要探讨认知修复方案对精神分裂症患者工作记忆缺陷的影响。精神分裂症是一种慢性、严重和使人衰弱的精神疾病。它通常被描述为阳性和阴性症状。工作记忆缺陷被认为是精神分裂症的主要认知特征。方法:采用有目的抽样方法,选取印度兰齐神经精神病学及相关科学研究所(RINPAS)收治的5例精神分裂症患者,年龄20 ~ 40岁,男性,符合ICD-10 DCR标准,最低受教育年限为12年。采用自行编制的社会人口学和临床数据表评估社会人口学相关因素,采用自行编制的阳性和阴性症状量表评估精神病症状,采用威斯康辛卡片分类测验和Stroop测验评估执行功能,采用韦氏记忆量表ii中的字母数字排序和空间跨度子测验评估被试的工作记忆。然后对他们进行为期三个月的认知补救计划,之后再进行测试,以观察干预计划的效果。结果:精神分裂症患者在接受认知修复治疗后,工作记忆能力有所改善。结论:认知修复方案对精神分裂症患者的执行功能,特别是工作记忆有积极的影响。
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