Relation between curability and tumor volume in a murine carcinoma and sarcoma.

J Shaeffer, A M El-Madhi, J Wakley
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引用次数: 3

Abstract

Tumor control doses (TCD50) using single 60CO doses were determined on C3HBA adenocarcinoma and Dunn osteosaroma ranging in size from microscopic pulmonary colonies (3 X 13(-5) mm3) to palpable subcutaneous tumors (300 mm3) in the hind limb. The power function TCD50 =23.57 TV0.15, with TCD50 in GY and TV (tumor volume) in mm3, fits the data for both tumors over the entire range of tumor volumes used.

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小鼠肿瘤和肉瘤的治愈率与肿瘤体积的关系。
使用单一60CO剂量测定C3HBA腺癌和Dunn骨香的肿瘤对照剂量(TCD50),其大小范围从显微镜下的肺部菌落(3 × 13(-5) mm3)到后肢可触及的皮下肿瘤(300 mm3)。幂函数TCD50 =23.57 TV0.15, TCD50以GY为单位,TV(肿瘤体积)以mm3为单位,可以在整个肿瘤体积范围内拟合两种肿瘤的数据。
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