Performance and acquisition of serial position sequences by pigeons as measures of behavioral toxicity.

Neurobehavioral toxicology Pub Date : 1979-01-01
D E McMillan
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Abstract

A procedure has been developed to measure the repeated acquisition of serial position sequences and to study the effects of drugs and toxic chemicals on the behavior generated by the procedure. Thus far experiments using the procedure have shown: (1) Performance schedules generate lower error rates than corresponding acquisition schedules: (2) Addition of a reset contingency further decreases errors under both performance and acquisition schedules: (3) Chained acquisition and performance schedules generate lower error rates than corresponding tandem acquisition and performance schedules: (4) Chained acquisition and performance schedules produce behavior that usually is more sensitive to drugs than corresponding tandem acquisition and performance schedules: (5) Acquisition schedules produce behavior that usually is more sensitive to drugs than corresponding performance schedules: and (6) Lead is an exception in that it produced clearer effects under a chained performance schedule with a reset contingency than under a corresponding acquisition schedule. The greater sensitivity to drug effects of behavior under acquisition schedules than behavior under performance schedules and of behavior under chained schedules may be a function of the baseline error rates, rather than the behavioral processes of acquisition, performance, and stimulus control.

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鸽子的表现和获得序列位置序列作为行为毒性的测量。
已经开发了一种程序来测量连续位置序列的重复获取,并研究药物和有毒化学物质对该程序产生的行为的影响。到目前为止,使用该过程的实验表明:(1)性能计划比相应的获取计划产生更低的错误率;(2)重置偶然性的增加进一步减少了性能和获取计划下的错误;(3)链式获取和性能计划比相应的串联获取和性能计划产生更低的错误率。(4)链式采购和绩效计划产生的行为通常比相应的串联采购和绩效计划对药物更敏感;(5)采购计划产生的行为通常比相应的绩效计划对药物更敏感;(6)铅是一个例外,因为它在带有重置偶发的链式绩效计划下产生的效果比在相应的采购计划下产生的效果更清晰。习得计划下的行为比表现计划下的行为和链式计划下的行为对药物效应更敏感,这可能是基线错误率的函数,而不是习得、表现和刺激控制的行为过程。
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