N‐arilação do imidazol via CuI: um tutorial para otimização de um sistema catalítico através do planejamento experimental

Abstract

This work deals the development of a catalytic system for the N‐arylation of imidazole with CuI through experimental design. 1,10‐Phenanthroline (bidentate ligand) was used and proved to be efficient in the coupling of iodo‐ and bromoarenes with imidazole. Thus, the article presented here is intended to serve as a tutorial for optimization of new catalytic systems and may be applied as a low‐cost practical class for chemistry undergraduate students.