Synthetic Organs For Transplant And Bio-mimicReactors For Process Intensification Using Nano-structured Micro-porous Materials

E. Akay, Z. Okumuş, O. S. Yildirim, M. Bokhari, G. Akay
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Abstract

In order to achieve Process Intensification through monolithic micro-reactors in bioand chemical technology we examined the processing strategy in the human body, taking the liver as a typical organ. The macroand micro-architectural structure can be mimicked by using nano-structured micro-porous polymers which were used as support in tissue engineering and bioprocess intensification. It was shown that these materials could be used as bone transplant and they are integrated into the body. Their integration could be predicted through in vitro experiments. Metallic versions of these structures with a hierarchy of pore size were produced in order to obtain catalytic bioor chemical reactors operating at high temperature and/or pressure.
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用纳米结构微孔材料制备移植器官及强化生物模拟反应器
为了通过生物化学技术中的单片微反应器实现过程强化,我们以肝脏为典型器官,研究了人体的加工策略。利用纳米微孔聚合物可以模拟其宏观和微观结构,并将其作为组织工程和生物过程强化的载体。结果表明,这些材料可用于骨移植,并与人体相结合。它们的结合可以通过体外实验来预测。为了获得在高温和/或高压下工作的催化生物或化学反应器,生产了具有孔隙大小等级的这些结构的金属版本。
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