The Comparison of Er α Expression Between Endometriosis with No Endometriosis

D. Irsat Syafardi, H. Siregar, Y. B. Kaban, E. Ardiansyah
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Abstract

Estrogen receptors (ER) play an important role in mediating action. The ER α has a higher affinity for estrogen and the dominant form of the normal endometrium. A cross-sectional study from an ectopic  tissue of endo-metriosis and normal was examined for immunohistochemistry. This research was conducted from November 2015 until the sample complete. The analysis was performed using Fisher Exact test, p <0.05 was considered to any difference of estrogen alpha receptor expression between endometriosis patients with no endometriosis. REα is more dominant in normal endometrium, whereas in the case of endometriosis in the presence of many negative expression of REα then the assumption that REβ is a receptor that many encountered. There is a dif-ference in the expression of REα between endometriosis with no endometriosis.
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子宫内膜异位症与无子宫内膜异位症Er α表达的比较
雌激素受体(ER)在其中起着重要的调节作用。ER α对雌激素和正常子宫内膜的优势形态有较高的亲和力。横断面研究从异位组织子宫内膜异位症和正常检查免疫组织化学。本研究从2015年11月开始,直至样本完成。采用Fisher精确检验进行分析,雌激素受体在子宫内膜异位症患者与非子宫内膜异位症患者之间的表达差异以p <0.05考虑。REα在正常子宫内膜中更占优势,而在子宫内膜异位症的情况下,存在许多REα的负表达,那么假设REβ是许多遇到的受体。REα在子宫内膜异位症与非子宫内膜异位症的表达有差异。
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